Erik Rose of Mozilla will reprise his PyCon presentation,Designing Poetic APIs. "The language you speak determines the thoughts you can think. Thus, API designers (and that includes you, if you've ever coined a function) have a great duty, as language inventors, to expand the mental canvases of those who come after. We'll concretize that into 7 hallmarks of good APIs, pulling examples (and bloopers) from popular Python libraries."
Lightning talks, 5 to 10 minutes extemporaneous expositions on a topic of interest to you, something you recently learned, kind of like a show and tell, are always welcome as well.